SAT-483 Levothyroxine Absorption Test: A Potential Therapeutic Tool for Levothyroxine Malabsorption
نویسندگان
چکیده
منابع مشابه
Clinical Application of the Levothyroxine Absorption Test in the Diagnosis of Pseudo-Malabsorption
We present a variation and clinical application of the Levothyroxine Absorption Test (LAT) in the identification of pseudo-malabsorption of levothyroxine in uncontrolled hypothyroidism, for which there is no current gold standard protocol, and a variety of methods proposed in the literature. The LAT was conducted over 5days with thyroid function tests conducted pre-LAT, then at day 1 and 5. The...
متن کاملLiquid levothyroxine and its potential use.
Traditionally, L-T4 has been available in tablet form as a stable salt that contains sodium; approximately 6090 % of the dose is absorbed in the jejunum and ileum within 3 hours of ingestion.6 Absorption is maximal when it is taken on an empty stomach, demonstrating the importance of gastric acidity in the process. In fact, the acid gastric pH is essential to dissolve the tablet, removing sodiu...
متن کاملRapid Levothyroxine Absorption Testing: A Case Series of Nonadherent Patients
BACKGROUND Nonadherence to levothyroxine therapy is one cause of persistent hypothyroidism. To distinguish nonadherence from malabsorption, a levothyroxine absorption test is required. Typically, this test measures the serum free thyroxine (FT4) response to 1000 mcg of oral levothyroxine over 4 to 24 hours. Published data indicate that serum levels of FT4 are at or near their peak 2 hours after...
متن کاملEffect of calcium carbonate on the absorption of levothyroxine.
CONTEXT The effect of calcium carbonate on the absorption of levothyroxine has not been studied systematically. Such a potential drug interaction merits investigation because concurrent treatment with both drugs is common, particularly in postmenopausal women. OBJECTIVE To investigate the potential interference of calcium carbonate in the absorption of levothyroxine. DESIGN Prospective coho...
متن کاملLevothyroxine in psychiatry: issues related to absorption after oral dosing.
J Clin Psychiatry 2013;74(8):e744–e746 (doi:10.4088/JCP.13f08668) © Copyright 2013 Physicians Postgraduate Press, Inc. T prevalence of hypothyroidism is about 0.3%; the disorder is more common with increasing age and in women relative to men.1 Subclinical hypothyroidism occurs in 4%–20% of adults, depending on the population studied and the disease definition applied.2 Clinical and subclinical ...
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ژورنال
عنوان ژورنال: Journal of the Endocrine Society
سال: 2020
ISSN: 2472-1972
DOI: 10.1210/jendso/bvaa046.1162